Updated: 08.11.2022 16:01:43




Broad spectrum of antibacterial activity

Colors the skin

Storage stability

May cause burns, burning

Long lasting effect

Cannot be used in thyroid disorders

Long term safety

Absence of addictive pathogens




Does not penetrate the skin

Skin coloring green

Approved for use during pregnancy

Burning sensation upon application

Used in pediatrics

Possible allergic reactions

One of the safest antiseptics

Cannot be combined with active iodine

Description of the antiseptic drug Iodine


Iodine is available as a solution for topical application to the wound surface. The tool is used for the purpose of antiseptic treatment of wounds. In medicine, a 5% alcohol solution is used. It is now being used less and less. Analogues come to replace — Lugol’s solution, Iodinol, Betadine.

An antiseptic prevents the entry of pathological microorganisms into the wound. It is applied around the wound, and not in its center, like many other antiseptics.

Iodine must be used carefully, as it burns. Good for disinfecting scratches, drying boils and pimples. The solution is used for dislocations, swelling, swelling, sprains. The iodine mesh prevents microbes from entering the wound.

Research and effectiveness

Antiseptics containing iodine, in particular Betadine, have a wide bactericidal spectrum of action. Means can be used for therapeutic and prophylactic purposes. Iodine is effective for treating fresh wounds, sutures, burns, and purulent lesions. It cannot be used in case of hypersensitivity to iodine and thyroid dysfunction.

Iodine is widely used in surgery for the treatment of hands and the treatment of infected wounds. Studies show that it quickly gives the desired effect. Within a week of using iodine preparations, the edema around the wound is removed, the pain disappears, and the release of purulent exudate decreases.

The substance retains its antiseptic properties for a long time in the presence of pus and blood. It rarely causes allergic reactions and does not cause toxic reactions with long-term use. Microorganisms do not develop resistance to the drug.

Source: Chernyakov A.V. «Modern antiseptics and surgical aspects of their use». 2017.


Iodine has the following restrictions on its use:

  1. nephrosis and nephritis;

  2. pulmonary tuberculosis;

  3. hemorrhagic diathesis;

  4. hypersensitivity to a substance;

  5. pregnancy;

  6. breast-feeding.

Iodine is incompatible with essential oils, ammonia, sedimentary white mercury. Alkaline and acidic environment, the presence of blood and pus somewhat weaken the effect of the solution.

Side effects

Topical application of iodine may cause symptoms of iodism. This is manifested by lacrimation, hypersalivation, metallic taste, rhinitis. Skin irritation may occur. With an extensive lesion, there is a risk of Quincke’s edema.


Iodine is applied around the damaged area. The frequency of application is determined individually. The solution is also used for washing lacunae — 4-5 procedures in 2-3 days. An antiseptic is used for instillation into the ear for 2-4 weeks. In surgery, iodine is prescribed for the treatment of postoperative wounds and burns.

Who suits

Iodine is used as an antiseptic for external use. It is suitable for infectious, purulent wounds and burns. Indicated for the prevention of infection and violation of the integrity of the skin. It is also able to reduce the severity of the inflammatory process in myositis and neuralgia.

The tool is used in the treatment of inflammatory diseases of the skin and mucous membranes. It has an irritating effect and can be used as a distraction in atherosclerosis. It is prescribed in the complex treatment of syphilis.

Description of Zelenka


Zelenka — antiseptic solution for the treatment of wounds, abrasions, postoperative sutures. Active against gram-positive microorganisms. It is a green liquid with a specific smell of alcohol.

The agent, when applied topically, does not penetrate the damaged skin, does not have a systemic effect. Safe to use for pregnant women and children.

Research and effectiveness

In Russia and other countries of the former USSR, brilliant green is used as an antiseptic. The antiseptic is destroyed in the European Union and the USA, but is practically not used, yielding to analogues with a large number of advantages.

In surgery, Zelenka serves as a solution for disinfecting instruments. As a medicine, a 1% and 2% solution is used. Also sold in pencil form for easy handling.

Zelenka is used to disinfect scars, abrasions, cuts. It is indicated for the treatment of pyoderma, blepharitis, boils, infections caused by staphylococci. Used for external processing only.

Zelenka is a part of the following antiseptics:

  1. bactericidal adhesive plasters;

  2. Novikov’s solution;

  3. corn fluid.


Zelenka is not used for hypersensitivity and allergies. It is not recommended to use the remedy for weeping bleeding wounds. It is forbidden to use for the treatment of mucous membranes. There is a risk of chemical burns to sensitive tissues. If Zelenka gets into the eyes, a chemical burn occurs.

Side effects

Zelenka is one of the safest antiseptics in the world. It is allowed to be used from the first day of life. Of the side effects, only allergic reactions are possible with intolerance to substances in the composition.


Zelenka is applied with cotton swabs or swabs to the affected area of ​​the skin. The agent treats the wound itself and healthy tissues around it. With open damage, only its edges are lubricated.

With blepharitis and meibomitis, the eyelids are treated. Zelenka must be applied carefully to avoid getting the solution into the eyes, as a burn is possible. The effectiveness of the remedy is reduced when there is blood in the wound.

Who suits

Zelenka’s solution can be used to treat fresh scars and abrasions. It is indicated for pyoderma, blepharitis. It is also used to prevent infection of healthy skin around the wound. Can be used for children, pregnant women and breastfeeding.

Cost and analogues






10 ml 5% — from 15 rubles


A 10% solution is used in dentistry, gynecology, surgery, traumatology. It is used to prepare for operations. Also available as vaginal suppositories for the treatment of mixed infections.


Based on the component of the same name, it has a pronounced bactericidal effect, does not irritate due to the absence of alcohol, and is not addictive with prolonged use.


A broad-spectrum antibacterial agent, it also has an anti-inflammatory effect. Used in surgery, venereology, obstetrics, proctology, otolaryngology.

Lugol’s solution:

A bactericidal preparation with a softening effect. It has an adverse effect on staphylococci, Escherichia coli, streptococci, Proteus and other gram-positive and gram-negative microorganisms


10 ml 1% — from 15 rubles

Substitutes —

Methylene blue:

It is used for the treatment of burns, purulent-inflammatory lesions, pyoderma. Does not apply up to 1 year.


A disinfectant with a wide spectrum of antimicrobial action, effective against fungal infections, staphylococci and streptococci, stops the inflammatory process.

Which drug is better

  1. Iodine is used for cauterization. Incorrect use of it can provoke unpleasant complications. Zelenka is safer in this regard. The advantage of Iodine is that the drug is suitable for the treatment of fungus, they can rinse the mouth and make face masks from it in order to get rid of acne.

  2. The main action of Zelenka is aimed at protecting the wound from moisture and bacteria. It has practically no contraindications and does not cause adverse reactions. When using iodine, headaches and pressure drops may occur. But when used correctly, it effectively reduces swelling and disinfects.

  3. Iodine should not be used for allergies and children. Zelenka in this case will be safe. It also helps stop bleeding and dries up the wound. Both remedies are indispensable for certain conditions and can complement each other’s action.

  4. Before using an antiseptic, you must carefully read the instructions. If adverse reactions occur, stop using the drug and consult a doctor.

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